The research activity of the Intense Laser Irradiation Laboratory (ILIL) is focused on fundamental studies of high-intensity laser interaction with matter and their applications. The Laboratory participates to the European Infrastructures EuPRAXIA, ELI and HiPER+. is part of the European consortium engaged in the laser-driven fusion research and a member of the Laserlab-Europe AISBL. Since 2022, the Lab is engaged in the implementation of the IPHOQS (Integrated Infrastructure in Photonics and Quantum Sciences) and EuAPS (EuPRAXIA Advanced Photon Sources) in the framework of the Italian Recovery and Resilience Plan (PNRR). ILIL is also part of the PNRR Tuscany Health Ecosystem “THE” for the development of novel radiation sources for Advanced Radiotherapy radiation sources. Fundamental studies include plasma formation and heating by intense laser beams, laser-induced instabilities and other non-linear processes, atomic physics of highly-ionised plasmas, ultrashort X-ray emission and acceleration of charged particles. The Laboratory has well established collaborations with many leading international High-Power Laser Laboratories and Facilities, as well as Academic Groups. ILIL has a long-term experience in the training of young scientists through several schemes including European Union RT Networks.